What is Trestolon?

Trestolone Also known as Testomax, Testosaur, RAD140, is a synthetic anabolic created in 2010 by Radius Pharmaceuticals. Its molecular formula is called 7α-methyl-19-nortestosterone (MENT)     

He got this name ending in “lonely”, most likely because it has aspects close to Primobolan ( Methenolone ) , one of the most famous anabolic steroids from the very beginning of resistance training. 

This anabolic was originally developed to prevent muscle loss, treat andropause (male menopause), prevent severe bone loss with age, and prevent breast cancer. 

It does not have the ability to bind to receptors in the prostate or vesicles, which makes its side effects on these organs virtually nil. Hence, this substance is much more anabolic than androgenic.

SARMs (Selective Estrogen Receptor Modulators) are very popular in the bodybuilding world among people who are looking for faster muscle gains but don’t want to use synthetic anabolic steroids. And among the most sought after SARMs is Trestolone.  More details: https://anabolicmenu.ws/global-anabolic-tres-50/

Trestolone is an experimental androgen and drug used for high levels of progesterone (a sex hormone needed to balance the ovarian cycle), which was originally developed based on the principle of male birth control and a replenisher for andropause. 

However, it has become clear that this drug can be used to improve aesthetic results in bodybuilding, increase dosage and promote fast and dense muscle gain, strength gains and other benefits with few side effects.

But what would Trestolon be? What are its effects? Why are athletes and bodybuilders using it so much? Could this cause a side effect? What are its main uses? Can women use it? 

You will find the answers to these questions in the article below.

Pharmacodynamics

As AAS, trestolone is an agonist of the androgen receptor (AR), by analogy with androgens , such as testosterone and dihydrotestosterone (DHT). Trestolone is not a substrate for 5α- reductase and therefore is not potentiated or inactivated in so-called “androgenic” tissues such as skin , hair follicles and prostate gland. Thus, it has a high ratio of anabolic to androgenic activity, like other nandrolone derivatives. Trestolone is a substrate for aromatase and therefore produces estrogen 7α- methylestradiol as a metabolite.

However trestolon has only a weak estrogenic activity and an amount that is apparently not enough for replacement therapy, as evidenced by a decrease in bone mineral density in men , taking him about hypogonadism . Trestolone also has strong progestogenic activity. It is believed that both the androgenic and progestogenic activity of trestolone are related to its antigonadotropic activity.

Pharmacokinetics

The pharmacokinetic properties of trestolone , such as poor oral bioavailability and short half-life , make it unsuitable for oral administration or long-term intramuscular injection. Thus, trestolone must be administered parenterally by another and more practical route, such as a subcutaneous implant, transdermal patch, or topical gel. Trestolone acetate, a prodrug of trestolone , can be administered intramuscularly.